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The HIV/AIDS study group, Research Center on Global Emerging and Re-emerging Infectious Diseases, Institute of Tropical Disease Universitas Airlangga successfully held a Policy Brief Dialogue with the theme “The Role of Antiretroviral Resistance Examination as an Effort to Control HIV Cases in Indonesia.” This activity was carried out in a hybrid manner at the Harris Hotel, Gubeng Surabaya, on Wednesday, October 19, 2022. It was attended by a great resource person, Prof. Dr. Nasronudin, dr. Sp.PD., KPTI-FINASIM as the director of Airlangga Hospital, and dr. Ratna Budi Hapsari M.KM as the HIV PIMS Hepatitis PISP work team of the Indonesian Ministry of Health. This activity was also attended by clinicians, researchers, non-governmental organizations, and policymakers. This activity aims to support the WHO program to end AIDS with a target of 95.95.95, which means 95% of people living with HIV know their HIV status, 95% of people who know their status on treatment, and 95% of people on treatment with suppressed viral loads. In addition, this activity is also to support the Indonesian Ministry of Health’s program named STOP (Educate, Test, Treat, and Maintain). Hopefully, this brief policy dialogue can provide recommendations to complement the achievements of handling HIV/AIDS in Indonesia.

Institute of Tropical Disease Universitas Airlangga successfully held a guest lecture with the topic “Investigation of COVID-19”. This activity was held in the Enlightenment Room 2nd Fl, ITD Unair, on Thursday, October 6, 2022. This activity presented a great resource person from Kobe University, Japan, Professor Yasuko Mori, MD., Ph.D. This activity was attended by ITD Unair staff and researchers. In this activity, Professor Yasuko Mori, MD., Ph.D. explained in detail the SARS-CoV-2 virus variant, vaccine doses, and comparison of neutralizing activities against VOCs 1-3 months after SARS-CoV-2 Infection. Hopefully, this guest lecture can provide more in-depth knowledge regarding the COVID-19 investigation.

Institute of Tropical Disease Universitas Airlangga held a Progress Report Meeting CRC-ERID In a collaboration between ITD Unair and Kobe University – Japan on Wednesday, October 5, 2022. This activity was carried out in Enlightenment Room 2 Fl – Institute of Tropical Disease. Before the COVID-19 pandemic, this Progress Report Meeting was usually held once in three months. However, due to the Covid-19 outbreak, this activity had stopped for almost three years. This activity was attended by Prof. Yasuko Mori, M.D., Ph.D., and Prof. Kazafumi Shimizu, Ph, D from Kobe University – Japan. The presentation of the progress report was carried out by representatives of the Dengue study group, Viral Diarrhea study group, Bacterial Gastroenteritis & Antimicrobial Resistance study groups, and the New Pathogens study group. The Progress Report Meeting is one form of a series of collaborations between the Institute of Tropical Disease Unair and Kobe University – Japan, which has entered the 3rd term, with a period of 5 years per term. As a result, CRC-ERID has produced many achievements, such as reputable international journals, research grants from internal and external Ph.D. students, and supporting laboratory activities with adequate equipment.

The Institute of Tropical Disease, Airlangga University, received a visit from the PUI-PT Center for Fintech and Banking, Sebelas Maret University on Friday, September 16, 2022. This visit was about exchanging best practices for managing the Center for Excellence in Science and Technology and strengthening relations between the Centers for Excellence in Science and Technology. This visit received a good response from the Institute of Tropical Disease Chairman, Prof. Maria Inge Lusida, Ph.D., and Secretary of ITD, Prof. Dr. Fedik Abdul Rantam, DVM. In addition, there were 15 participants from the PUI-PT Center for Fintech and Banking at Sebelas Maret University. Dr. Taufiq Arifin, Ph.D., describes the profiles, innovations, collaborations, and publications carried out by the PUI-PT Center for Fintech and Banking, Sebelas Maret University.

Institute of Tropical disease Universitas Airlangga, on Wednesday, September 14, 2022, received a visit from Prof. Takuya Fukushima of the Laboratory of Hematoimmunology, Graduate School of Health Sciences, University of the Ryukyus, Okinawa, Japan. This activity discusses the cooperation and collaboration between the HIV Laboratory of ITD Unair and the University of the Ryukyus, Okinawa, Japan. This collaboration received a good response from Prof. Maria Inge Lusida, Ph.D. This collaboration discusses the molecular epidemiological surveillance of the Human T-Cell Leukemia Virus (HTLV-1). We hope that this collaboration can be successful.

Institute of Tropical Disease Universitas Airlangga received a visit from “One Health Student Club Batch 3” on Tuesday, September 13, 2022. This activity was carried out in a hybrid. This activity is a means of education and introduction to OHSC Batch 3 members about the facilities owned by ITD and the role of ITD in research. This visit received a good response from Prof. Maria Inge Lusida, Ph.D., the head of ITD Unair. This activity was also attended by the coordinator of ADPRC-OHCC, Prof. Dr. dr. Fedik Abdul Rantam. The activity was an introduction to ITD, which the head delivered of Human Resources of ITD Unair Laura Navika Yamani, S.Si., M.Sc., Ph.D. During this visit, OHSC Batch 3 members also conducted laboratory visits to the Malaria Laboratory, Dengue Laboratory, and TB Laboratory.

Students of the Medical Study Program, Faculty of Medicine, Universitas Airlangga visited the Institute of Tropical Disease, Universitas Airlangga, to learn the Block System of Hematology and Immunology. This activity is carried out online. Students are introduced to the Institute of Tropical Disease as a place for biomolecular research. This visit was carried out for two days: Friday, September 2, 2022, and Tuesday, September 6, 2022. This visit introduced various activities carried out by each laboratory, workshops, research, etc. Hopefully, this activity can add information and insight about hematology and immunology.

Friday, September 2, 2022, Viral Diarrhea Study Group Research Center on Global Emerging and Re-emerging Infectious Diseases, Institute of Tropical Disease Universitas Airlangga, successfully held an international workshop on the topic “Introduction to Conventional Cloning and Mutagenesis PCR in Molecular Biology Application.” This material was presented by dr. Reza Gandi Bawono, MD., Ph.D. This material explains DNA cloning and gene mutagenesis. He explained the stages of how to do DNA cloning from beginning to end. After that, he explained what mutagenesis was and the steps. This workshop also featured many wet laboratory simulations. This workshop was attended by the chairman of ITD, Prof. Maria Inge Lusida, Ph.D., and the head of RC-GERID, Laura Navika Yamani, S.Si., M.Sc., Ph.D. Hopefully, the knowledge presented can add new knowledge and be implemented in research so that the existing expertise continues to grow.

From 30 to 31 September 2022, the Institute of Tropical Disease Universitas Airlangga received a visit from Surabaya Health Polytechnic students for the Molecular Biology Practicum. Prof. Ahmad Yudianto welcomed this event as the Head of the Human Genetics Study Group of the Molecular Forensic Division, who previously provided material on Molecular Biology online. On the first day, Surabaya Health Polytechnic students performed DNA extraction and PCR in the Human Genetics Laboratory alternately by dividing into two small groups so that the practicum and giving instructions were more conducive. On the second day, they continued with the next practicum stage, namely electrophoresis at the Human Genetics Laboratory, followed by posttest and closing practicum activities. Hopefully, this event can provide learning opportunities and experiences for students in conducting DNA testing so that the knowledge gained can be helpful for their field in the future.

Breast cancer is one of the worst diseases that affect women. Long-term treatment with therapy or surgery has a detrimental effect on the patient. Breast cancer is caused by unregulated cell growth and has a high mortality rate. Many researchers are working to develop effective, efficient, safe, and available treatments for everyone. Kappaphycus alvarezii algae have been in great demand as a breast cancer drug because it contains chemicals that are expected to be anti-cancer. This paper aims to see how secondary metabolites in algae interact with Nuclear Factor-kappaB protein kinase in breast cancer. Ligands and proteins were obtained from PubChem and PDB websites, respectively. Swiss ADME was then used to assess Pharmacokinetic and Drug similarity properties. The final stage involves using molecular docking with PyRx and molecular dynamics to identify interactions and visualize between ligands and target proteins. The test findings revealed that the chemical marinol has the superior binding capacity to the protein kinase NF kB because it has a chromone group that controls transport efficiently in preventing breast cancer proliferation. The QSAR analysis revealed that marinol has various anti-cancer properties, not only in breast cancer but also in other cancers. Because it has a chromone group, the test results showed that marinol has relatively high effectiveness as an anti-breast cancer agent, with a binding energy of -7.5 kcal/mol. Authors: Teguh Hari Sucipto, Alyaa Farrah Dibha, Rahadian Zainul, et al. Article Title: Utilization of Secondary Metabolites in Algae Kappaphycus alvarezii as a Breast Cancer Drug with a Computational Method Detailed information about this scientific article can be found at: https://phcogj.com/article/1800 Source: news.unair.ac.id Picture Source: Detik.com